Oral ulcers hide rheumatism “crisis”
Yang Chengde, a professor of rheumatology at Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine, reminded that in view of the complex clinical manifestations of Behcet’s disease and the severity of the disease, the patients who suspected that their oral ulcers were 鈥渦nusual鈥?should arrive in time.Hospital visit.
銆€銆€Question: oral ulcers are a must see rheumatology section Miss Zhang works in the media, has repeatedly visited the dentistry, treated with simple oral ulcers, but the effect is not good.
A few days ago, Miss Zhang went to the hospital again because of a recurrence of oral ulcers.
銆€銆€After asking her medical history in detail, the doctor did not prescribe her medicine, but suggested that she go to the rheumatology department to see.
After a thorough examination, Miss Zhang was diagnosed as “Bessel disease.”
Yang Chengde said that Behcet’s disease is an autoimmune disease characterized by “ulcer” rather than general oral ulcers.
銆€銆€Miss Zhang is very puzzled: how can oral ulcers be related to “immunity”?
What is Behcet’s disease?
Can you treat it?
Reminder: Behcet’s disease is the first symptom of oral ulcers.
銆€銆€Behcet’s disease is a systemic chronic disease that occurs mostly in young adults and is characterized by recurrent oral ulcers, genital ulcers, skin and eye lesions.
Behcet’s disease is not a “new disease.” As early as BC, the ancient Greek philosophy and medical scientist Hippocrates described the disease, but because of its low incidence, the public did not know much about it.
Epidemiological data show that most cases of Behcet’s disease are concentrated in countries along the Silk Road in East Asia, the Middle East, and the Mediterranean, and there are very few European and American countries.
In Japan, the prevalence of the disease is 10-15/100,000. In northern China, the prevalence of the disease is not less than 14/100,000.
銆€銆€Oral ulcers are usually the first symptom of Behcet’s disease and are not much different from normal recurrent oral ulcers.
Ulcers are multiple (generally 3 to 5), often involving soft palate and oropharynx, with severe pain.
銆€銆€Beginning as a “small nodule”, it quickly developed into a rice-to-soya-sized ulcer, round or irregular, with clear but irregular edges and varying shades. The bottom of the ulcer may have a pale yellow covering with a red glow around it.
銆€銆€At the same time, 80% of Behcet’s patients have genital ulcers (male patients mainly occur in the scrotum and penis, female patients mainly occur in the labia, vagina and cervix), generally deeper and larger than the oral ulcers, a small number, painThe play is slow to heal.
銆€銆€In addition to ulcers, the disease can also affect various systems of the body, such as the eyeball (anterior uveitis), joints (50% of patients have arthritis), the nervous system (5% of patients have neurological lesions), and the heart (valve damage), myocarditis, pericarditis), blood vessels (thrombophlebitis, venous thrombosis), gastrointestinal tract (dyspepsia, constipation, gastrointestinal ulcers), kidney (glomerulonephritis, amyloidosis), skin (nodules)Red spot, acne-like, papular lesions, etc.
銆€銆€Many patients and primary doctors do not have the “string” of Behcet’s disease in their brains. Therefore, it is easy to treat the oral ulcer of Behcet’s disease as a normal oral ulcer, which leads to the patient’s long-term lack of clear diagnosis and correct treatment.Delayed the best treatment opportunity.
銆€銆€At present, as long as there is oral ulcers, plus genital ulcers, eye damage (anterior uveitis, posterior uveitis or retinal vasculitis), skin damage (nodular erythema, pseudo folliculitis, papule pusBlister-like lesions, acne-like nodules after puberty) and positive acupuncture reactions (intradermal acupuncture or injection of saline for 24-48 hours, injection or acupuncture at the skin to form papules or pustules, diameter > 2 mm)Two of the four points can be diagnosed as Behcet’s disease.
銆€銆€In view of the complex clinical manifestations of Behcet’s disease and the severity of the disease among the individuals, patients who suspect that their oral ulcers are “unusual” should go to the hospital in time.